The following players performed superbly in real life this week and earned an upgraded “in form” card in this year’s FIFA 22 Video game. The following are the TOTW (Team of the Week) players for week 2 of the FIFA video game campaign. Look for SIF (second in form) and TIF (top in form) cards from these same players later this year. The campaign concludes with TOTY (team of the year) as the domestic and champions league campaigns reach their conclusion.
FIFA 22 TOTW 2 players are available from September 29 (6pm UK) until October 6, 2021 (6pm UK) in the FUT 22 packs.
| Position | Name | Club | Country | Rating |
| GK | Lukáš Hrádecký | Bayer 04 Leverkusen | FI | 85 |
| CB | Aritz Elustondo | Real Sociedad | ES | 82 |
| RB | Jesús Navas | Sevilla FC | ES | 86 |
| LB | Sergiño Dest | FC Barcelona | US | 81 |
| CM | Nicolò Barella | Inter | IT | 86 |
| CAM | Christopher Nkunku | RB Leipzig | FR | 84 |
| CDM | Denis Zakaria | Borussia M’gladbach | CH | 83 |
| RW | Gabriel Jesus | Manchester City | BR | 86 |
| RW | Felipe Anderson | Latium | BR | 84 |
| CF | Karim Benzema | Real Madrid | FR | 90 |
| ST | Victor Osimhen | Napoli | NG | 83 |
| Substitutes and Reserves | ||||
| GK | Benoît Costil | Bordeaux | FR | 82 |
| CM | Seko Fofana | Racing Club de Lens | CI | 82 |
| ST | Paul Onuachu | KRC Genk | NG | 82 |
| ST | Stefano Okaka | Medipol Başakşehir FK | IT | 81 |
| ST | Arthur Cabral | FC Basel | BR | 81 |
| LM | Emile Smith Rowe | Arsenal | EN | 81 |
| CB | Kortney Hause | Aston Villa | EN | 81 |
| ST | Gianluca Lapadula | Benevento | PE | 79 |
| LM | Ben Brereton | Blackburn Rovers | CL | 78 |
| CM | Pelle van Amersfoort | Cracovia | NL | 76 |
| CB | Linus Wahlqvist | IFK Norrköping | SE | 76 |
| ST | Gustaf Nilsson | SV Wehen-Wiesbaden | SE | 74 |